SFB 1278 – PolyTarget
Polymer-based nanoparticle libraries for targeted anti-inflammatory strategies

The goal of the Collaborative Research Center PolyTarget is to develop polymer-based, nanoparticulate carrier materials for pharmaceutically active ingredients for targeted therapy of diseases and syndromes, whose morbidity is characterized by an inflammatory reaction. With the aid of systematic particle libraries, structure-property relationships of polymers or nanoparticles and their biological effects are to be determined. New functional polymers are being developed to produce the nanoparticles (e.g., polyester amides, polyketals, functionalized polysaccharides, cationic polymers), tailor-made for the anti-inflammatory agent to be included. Close cooperation within the multi- and interdisciplinary consortium with researchers from Chemistry, Materials Science, Biology, Pharmacy and Medicine offers unique prerequisites for transferring the findings from basic research into applications. All PIs of PolyTarget are members of the Jena Center for Soft Matter (JCSM).